Effects of n-3 fatty acids on cartilage metabolism
نویسندگان
چکیده
منابع مشابه
Effects of n-3 fatty acids on cartilage metabolism.
Although the clinical benefits of dietary supplementation with n-3 polyunsaturated fatty acids (PUFA) has been recognised for a number of years, the molecular mechanisms by which particular PUFA affect metabolism of cells within the synovial joint tissues are not understood. This study set out to investigate how n-3 PUFA and other classes of fatty acids affect both degradative and inflammatory ...
متن کاملEffects of N-3 Fatty Acids on Chondrocyte Signalling Pathways
Introduction Previous studies within our laboratory have shown that supplementation of polyunsaturated n-3 fatty acids (PUFAs), but not other fatty acids have a beneficial effect on reducing the expression and activity of degradative and inflammatory factors known to cause damage and destruction of cartilage in arthritic diseases (1). Data has shown that the expression and activity of degradati...
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Decreased consumption of n-3 fatty acids (FA) and diets rich in animal proteins, saturated fats and n-6 vegetable oils are associated with a higher incidence of cardiovascular disease (CVD), certain malignancies and autoimmune disorders such as rheumatoid arthritis and Systemic Lupus Erythematosus (SLE), and renal disease. Recent studies show that reduced calorie intake and supplementation of d...
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N-3 polyunsaturated fatty acids (PUFAs) including α-linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have anti-inflammatory effects and neuronal protective functions and may benefit prevention of dementia; however, the epidemiological evidence is very limited. Therefore, the literature about the association between n-3 PUFA and dementia was searched, by using Pub...
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Adipose tissue and its secreted products, adipokines, have a major role in the development of obesity-associated metabolic derangements including Type 2 diabetes. Conversely, obesity and its metabolic sequelae may be counteracted by modulating metabolism and secretory functions of adipose tissue. LC-PUFAs (long-chain polyunsaturated fatty acids) of the n-3 series, namely DHA (docosahexaenoic ac...
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ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 2006
ISSN: 0029-6651,1475-2719
DOI: 10.1079/pns2006522